Tarling-Vallim Research Lab

Welcome to the Tarling and Vallim Labs 

Studying how cells and tissues adapt to changes in lipids in healthy and diseased states

 

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Tarling Lab

The Tarling Lab is focused on uncovering molecular mechanisms involved in maintaining cholesterol trafficking and homeostasis in immune cells in cardiopulmonary diseases.

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Vallim Lab

The Vallim Lab is interested in identifying novel regulators of lipid metabolism in metabolic disease using a combination of global -omics and gene-targeted approaches.

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News

April 2023 – We welcome our newest graduate student, Rochelle Lai, to the lab!

March 2023 – Liz is awarded an AHA Established Investigator Award!

January 2023 – The ETV is celebrating a BIG anniversary (10 years) this year! Lots of fun things planned throughout the year

December 2022 – We ended the year in the best way with an NOA for a new MPI R01 to study the gut-liver axis in cardiovascular disease!

Cover of Circulation Research journal.

Featured Publications

Take a look at our newest publication in Circulation Research, RNF130 Regulates LDLR Availability and Plasma LDL Cholesterol Levels, where we find that the membrane-bound E3 ubiquitin ligase RNF130 regulates the abundance and availability of LDLR at the plasma membrane.

Check out our study published in Nature, An integrative systems genetic analysis of mammalian lipid metabolism, where we identify novel lipid biomarkers that predict the accumulation of pathological lipids in the livers of mice and humans.